S3 as a cover of S3 branched over a knot

A Filesystem using Amazon S3

We propose a system that uses cloud storage as an hourly back-up system while providing a fully featured filesystem for distributed storage. We mount a fully featured filesystem stored in the cloud to a local server and take advantage of a very large local server cache so that we can have similar performance to a central local server while having the reliability of a cloud system. We use a modi...

Text S3

We sought to characterize WPEC by quantifying per-hour log-fold change. To do so, we regressed the log gene expression on time (hour) and extracted the linear slope. For genes with monotonically increasing or decreasing expression trajectories, the utility of our WPEC measure to discriminate is obvious. Our WPEC measure can also discriminate with more complex trajectories which may be reflectiv...

S3 Table

study design, analysis and interpretation The following table summarizes several key concepts relating to sample preparation and library construction that may influence analysis and interpretation of RNA-seq data. Several initiatives are underway to develop standards and best practices that cover many of these concepts. These include: the Sequencing Quality Control (SEQC) consortium [2], the En...

S3 Text

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We estimated clinic-averaged co-ancestries from WGS data assuming SNPs were both linked and unlinked. Linked analyses require a recombination file specifying distances between SNPs. We used a uniform recombination rate equal to 7.4 × 10−7 Morgans per base pair (Miles et al. 2016), the same as that specified in hmmIBD (Schaffner et al., n.d.). ChromoPainter essentially treats each unlinked SNP a...